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KRIT1 Regulates the Homeostasis of Intracellular Reactive Oxygen Species

KRIT1 is a gene responsible for Cerebral Cavernous Malformations (CCM), a major cerebrovascular disease characterized by abnormally enlarged and leaky capillaries that predispose to seizures, focal neurological deficits, and fatal intracerebral hemorrhage. Comprehensive analysis of the KRIT1 gene in...

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Detalles Bibliográficos
Autores principales: Goitre, Luca, Balzac, Fiorella, Degani, Simona, Degan, Paolo, Marchi, Saverio, Pinton, Paolo, Retta, Saverio Francesco
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910502/
https://www.ncbi.nlm.nih.gov/pubmed/20668652
http://dx.doi.org/10.1371/journal.pone.0011786