Hypernitrosylated ryanodine receptor/calcium release channels are leaky in dystrophic muscle

Duchenne muscular dystrophy (DMD) is characterized by progressive muscle weakness and early death resulting from dystrophin deficiency. Loss of dystrophin results in disruption of a large dystrophin glycoprotein complex (DGC) leading to pathologic calcium (Ca(2+))-dependent signals that damage muscl...

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Detalles Bibliográficos
Autores principales: Bellinger, Andrew M., Reiken, Steven, Carlson, Christian, Mongillo, Marco, Liu, Xiaoping, Rothman, Lisa, Matecki, Stefan, Lacampagne, Alain, Marks, Andrew R.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910579/
https://www.ncbi.nlm.nih.gov/pubmed/19198614
http://dx.doi.org/10.1038/nm.1916

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910579/
https://www.ncbi.nlm.nih.gov/pubmed/19198614
http://dx.doi.org/10.1038/nm.1916

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