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Structure of the CaMKIIδ/Calmodulin Complex Reveals the Molecular Mechanism of CaMKII Kinase Activation

Long-term potentiation (LTP), a long-lasting enhancement in communication between neurons, is considered to be the major cellular mechanism underlying learning and memory. LTP triggers high-frequency calcium pulses that result in the activation of Calcium/Calmodulin (CaM)-dependent kinase II (CaMKII...

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Detalles Bibliográficos
Autores principales: Rellos, Peter, Pike, Ashley C. W., Niesen, Frank H., Salah, Eidarus, Lee, Wen Hwa, von Delft, Frank, Knapp, Stefan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910593/
https://www.ncbi.nlm.nih.gov/pubmed/20668654
http://dx.doi.org/10.1371/journal.pbio.1000426