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Structure of the CaMKIIδ/Calmodulin Complex Reveals the Molecular Mechanism of CaMKII Kinase Activation
Long-term potentiation (LTP), a long-lasting enhancement in communication between neurons, is considered to be the major cellular mechanism underlying learning and memory. LTP triggers high-frequency calcium pulses that result in the activation of Calcium/Calmodulin (CaM)-dependent kinase II (CaMKII...
Autores principales: | Rellos, Peter, Pike, Ashley C. W., Niesen, Frank H., Salah, Eidarus, Lee, Wen Hwa, von Delft, Frank, Knapp, Stefan |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910593/ https://www.ncbi.nlm.nih.gov/pubmed/20668654 http://dx.doi.org/10.1371/journal.pbio.1000426 |
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