Associations between tamoxifen, estrogens, and FSH serum levels during steady state tamoxifen treatment of postmenopausal women with breast cancer

BACKGROUND: The cytochrome P450 (CYP) enzymes 2C19, 2D6, and 3A5 are responsible for converting the selective estrogen receptor modulator (SERM), tamoxifen to its active metabolites 4-hydroxy-tamoxifen (4OHtam) and 4-hydroxy-N-demethyltamoxifen (4OHNDtam, endoxifen). Inter-individual variations of t...

Descripción completa

Detalles Bibliográficos
Autores principales: Gjerde, Jennifer, Geisler, Jürgen, Lundgren, Steinar, Ekse, Dagfinn, Varhaug, Jan Erik, Mellgren, Gunnar, Steen, Vidar M, Lien, Ernst A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910688/
https://www.ncbi.nlm.nih.gov/pubmed/20565970
http://dx.doi.org/10.1186/1471-2407-10-313

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910688/
https://www.ncbi.nlm.nih.gov/pubmed/20565970
http://dx.doi.org/10.1186/1471-2407-10-313

Ejemplares similares