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Development and Validation of a Quantitative, High-Throughput, Fluorescent-Based Bioassay to Detect Schistosoma Viability

BACKGROUND: Schistosomiasis, caused by infection with the blood fluke Schistosoma, is responsible for greater than 200,000 human deaths per annum. Objective high-throughput screens for detecting novel anti-schistosomal targets will drive ‘genome to drug’ lead translational science at an unprecedente...

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Detalles Bibliográficos
Autores principales: Peak, Emily, Chalmers, Iain W., Hoffmann, Karl F.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910722/
https://www.ncbi.nlm.nih.gov/pubmed/20668553
http://dx.doi.org/10.1371/journal.pntd.0000759