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Highly Pathogenic H5N1 Influenza Viruses Carry Virulence Determinants beyond the Polybasic Hemagglutinin Cleavage Site

Highly pathogenic avian influenza viruses (HPAIV) originate from avirulent precursors but differ from all other influenza viruses by the presence of a polybasic cleavage site in their hemagglutinins (HA) of subtype H5 or H7. In this study, we investigated the ability of a low-pathogenic avian H5N1 s...

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Detalles Bibliográficos
Autores principales: Bogs, Jessica, Veits, Jutta, Gohrbandt, Sandra, Hundt, Jana, Stech, Olga, Breithaupt, Angele, Teifke, Jens P., Mettenleiter, Thomas C., Stech, Jürgen
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910732/
https://www.ncbi.nlm.nih.gov/pubmed/20676399
http://dx.doi.org/10.1371/journal.pone.0011826