Deterioration of glomerular endothelial surface layer induced by oxidative stress is implicated in altered permeability of macromolecules in Zucker fatty rats

AIMS/HYPOTHESIS: The glomerular endothelial layer is coated by the endothelial surface layer (ESL), which is suggested to play a role in regulation of the permselectivity of macromolecules. Production of heparanase, a degrading enzyme of the ESL, is induced by reactive oxygen species (ROS). We hypot...

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Detalles Bibliográficos
Autores principales: Kuwabara, A., Satoh, M., Tomita, N., Sasaki, T., Kashihara, N.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910881/
https://www.ncbi.nlm.nih.gov/pubmed/20526760
http://dx.doi.org/10.1007/s00125-010-1810-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910881/
https://www.ncbi.nlm.nih.gov/pubmed/20526760
http://dx.doi.org/10.1007/s00125-010-1810-0

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