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A Re-evaluation of the “Oncogenic” Nature of Wnt/β-catenin Signaling in Melanoma and Other Cancers

In cancer, Wnt/β-catenin signaling is ubiquitously referred to as an “oncogenic” pathway that promotes tumor progression. This review examines how the regulation and downstream effects of Wnt/β-catenin signaling in cancer varies depending on cellular context, with a focus on malignant melanoma. We e...

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Detalles Bibliográficos
Autores principales: Lucero, Olivia M., Dawson, David W., Moon, Randall T., Chien, Andy J.
Formato: Texto
Lenguaje:English
Publicado: Current Science Inc. 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910886/
https://www.ncbi.nlm.nih.gov/pubmed/20603725
http://dx.doi.org/10.1007/s11912-010-0114-3