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Decreased Circulating Progenitor Cell Number and Failed Mechanisms of Stromal Cell-Derived Factor-1α Mediated Bone Marrow Mobilization Impair Diabetic Tissue Repair

OBJECTIVE: Progenitor cells (PCs) contribute to postnatal neovascularization and tissue repair. Here, we explore the mechanism contributing to decreased diabetic circulating PC number and propose a novel treatment to restore circulating PC number, peripheral neovascularization, and tissue healing. R...

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Detalles Bibliográficos
Autores principales: Tepper, Oren M., Carr, Jacquelyn, Allen, Robert J., Chang, Christopher C., Lin, Clarence D., Tanaka, Rica, Gupta, Sanjeev M., Levine, Jamie P., Saadeh, Pierre B., Warren, Stephen M.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911062/
https://www.ncbi.nlm.nih.gov/pubmed/20484135
http://dx.doi.org/10.2337/db09-0185