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Decreased Circulating Progenitor Cell Number and Failed Mechanisms of Stromal Cell-Derived Factor-1α Mediated Bone Marrow Mobilization Impair Diabetic Tissue Repair
OBJECTIVE: Progenitor cells (PCs) contribute to postnatal neovascularization and tissue repair. Here, we explore the mechanism contributing to decreased diabetic circulating PC number and propose a novel treatment to restore circulating PC number, peripheral neovascularization, and tissue healing. R...
Autores principales: | Tepper, Oren M., Carr, Jacquelyn, Allen, Robert J., Chang, Christopher C., Lin, Clarence D., Tanaka, Rica, Gupta, Sanjeev M., Levine, Jamie P., Saadeh, Pierre B., Warren, Stephen M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911062/ https://www.ncbi.nlm.nih.gov/pubmed/20484135 http://dx.doi.org/10.2337/db09-0185 |
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