Leptin Directly Depolarizes Preproglucagon Neurons in the Nucleus Tractus Solitarius: Electrical Properties of Glucagon-Like Peptide 1 Neurons

OBJECTIVE: Glucagon-like peptide (GLP)-1 inhibits food intake, acting both in the periphery and within the central nervous system. It is unclear if gut-derived GLP-1 can enter the brain, or whether GLP-1 from preproglucagon (PPG) cells in the lower brainstem is required to activate central GLP-1 rec...

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Detalles Bibliográficos
Autores principales: Hisadome, Kazunari, Reimann, Frank, Gribble, Fiona M., Trapp, Stefan
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911066/
https://www.ncbi.nlm.nih.gov/pubmed/20522593
http://dx.doi.org/10.2337/db10-0128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911066/
https://www.ncbi.nlm.nih.gov/pubmed/20522593
http://dx.doi.org/10.2337/db10-0128

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