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Design and evaluation of genome-wide libraries for RNA interference screens

RNA interference (RNAi) screens have enabled the systematic analysis of many biological processes in cultured cells and whole organisms. The success of such screens and the interpretation of the data depend on the stringent design of RNAi libraries. We describe and validate NEXT-RNAi, a software for...

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Detalles Bibliográficos
Autores principales: Horn, Thomas, Sandmann, Thomas, Boutros, Michael
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911109/
https://www.ncbi.nlm.nih.gov/pubmed/20550664
http://dx.doi.org/10.1186/gb-2010-11-6-r61