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Detection and analysis of alternative splicing in Yarrowia lipolytica reveal structural constraints facilitating nonsense-mediated decay of intron-retaining transcripts

BACKGROUND: Hemiascomycetous yeasts have intron-poor genomes with very few cases of alternative splicing. Most of the reported examples result from intron retention in Saccharomyces cerevisiae and some have been shown to be functionally significant. Here we used transcriptome-wide approaches to eval...

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Detalles Bibliográficos
Autores principales: Mekouar, Meryem, Blanc-Lenfle, Isabelle, Ozanne, Christophe, Da Silva, Corinne, Cruaud, Corinne, Wincker, Patrick, Gaillardin, Claude, Neuvéglise, Cécile
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911113/
https://www.ncbi.nlm.nih.gov/pubmed/20573210
http://dx.doi.org/10.1186/gb-2010-11-6-r65