Intranasal M Cell Uptake of Nanoparticles Is Independently Influenced by Targeting Ligands and Buffer Ionic Strength

In mucosal tissues, epithelial M cells capture and transport microbes across the barrier to underlying immune cells. Previous studies suggested that high affinity ligands targeting M cells may be used to deliver mucosal vaccines; here, we show that particle composition and dispersion buffer ionic st...

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Detalles Bibliográficos
Autores principales: Rajapaksa, Thejani E., Bennett, Kaila M., Hamer, Mary, Lytle, Christian, Rodgers, Victor G. J., Lo, David D.
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Molecular Bases of Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911333/
https://www.ncbi.nlm.nih.gov/pubmed/20511224
http://dx.doi.org/10.1074/jbc.M110.126359

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911333/
https://www.ncbi.nlm.nih.gov/pubmed/20511224
http://dx.doi.org/10.1074/jbc.M110.126359

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