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Intranasal M Cell Uptake of Nanoparticles Is Independently Influenced by Targeting Ligands and Buffer Ionic Strength
In mucosal tissues, epithelial M cells capture and transport microbes across the barrier to underlying immune cells. Previous studies suggested that high affinity ligands targeting M cells may be used to deliver mucosal vaccines; here, we show that particle composition and dispersion buffer ionic st...
Autores principales: | Rajapaksa, Thejani E., Bennett, Kaila M., Hamer, Mary, Lytle, Christian, Rodgers, Victor G. J., Lo, David D. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911333/ https://www.ncbi.nlm.nih.gov/pubmed/20511224 http://dx.doi.org/10.1074/jbc.M110.126359 |
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