Different Susceptibility to the Parkinson's Toxin MPTP in Mice Lacking the Redox Master Regulator Nrf2 or Its Target Gene Heme Oxygenase-1

BACKGROUND: The transcription factor Nrf2 (NF-E2-related factor 2) and its target gene products, including heme oxygenase-1 (HO-1), elicit an antioxidant response that may have therapeutic value for Parkinson's disease (PD). However, HO-1 protein levels are increased in dopaminergic neurons of...

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Detalles Bibliográficos
Autores principales: Innamorato, Nadia G., Jazwa, Agnieszka, Rojo, Ana I., García, Concepción, Fernández-Ruiz, Javier, Grochot–Przeczek, Anna, Stachurska, Anna, Jozkowicz, Alicja, Dulak, Jozef, Cuadrado, Antonio
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911386/
https://www.ncbi.nlm.nih.gov/pubmed/20676377
http://dx.doi.org/10.1371/journal.pone.0011838

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911386/
https://www.ncbi.nlm.nih.gov/pubmed/20676377
http://dx.doi.org/10.1371/journal.pone.0011838

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