EGFR/Met association regulates EGFR TKI resistance in breast cancer

Breast cancers show a lack of response to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs), despite 30% of tumors expressing EGFR. The mechanism of this resistance is unknown; however, we have recently shown that Met kinase activity compensates for loss of EGFR kinase activi...

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Detalles Bibliográficos
Autores principales: Mueller, Kelly L, Yang, Zeng-Quan, Haddad, Ramsi, Ethier, Stephen P, Boerner, Julie L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911419/
https://www.ncbi.nlm.nih.gov/pubmed/20624308
http://dx.doi.org/10.1186/1750-2187-5-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911419/
https://www.ncbi.nlm.nih.gov/pubmed/20624308
http://dx.doi.org/10.1186/1750-2187-5-8

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