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Interaction between circulating galectin-3 and cancer-associated MUC1 enhances tumour cell homotypic aggregation and prevents anoikis

BACKGROUND: Formation of tumour cell aggregation/emboli prolongs the survival of circulating tumour cells in the circulation, enhances their physical trapping in the micro-vasculature and thus increases metastatic spread of the cancer cells to remote sites. RESULTS: It shows here that the presence o...

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Detalles Bibliográficos
Autores principales: Zhao, Qicheng, Barclay, Monica, Hilkens, John, Guo, Xiuli, Barrow, Hannah, Rhodes, Jonathan M, Yu, Lu-Gang
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911446/
https://www.ncbi.nlm.nih.gov/pubmed/20565834
http://dx.doi.org/10.1186/1476-4598-9-154