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Interaction between circulating galectin-3 and cancer-associated MUC1 enhances tumour cell homotypic aggregation and prevents anoikis
BACKGROUND: Formation of tumour cell aggregation/emboli prolongs the survival of circulating tumour cells in the circulation, enhances their physical trapping in the micro-vasculature and thus increases metastatic spread of the cancer cells to remote sites. RESULTS: It shows here that the presence o...
Autores principales: | Zhao, Qicheng, Barclay, Monica, Hilkens, John, Guo, Xiuli, Barrow, Hannah, Rhodes, Jonathan M, Yu, Lu-Gang |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911446/ https://www.ncbi.nlm.nih.gov/pubmed/20565834 http://dx.doi.org/10.1186/1476-4598-9-154 |
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