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A factor model to analyze heterogeneity in gene expression

BACKGROUND: Microarray technology allows the simultaneous analysis of thousands of genes within a single experiment. Significance analyses of transcriptomic data ignore the gene dependence structure. This leads to correlation among test statistics which affects a strong control of the false discover...

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Detalles Bibliográficos
Autores principales: Blum, Yuna, Le Mignon, Guillaume, Lagarrigue, Sandrine, Causeur, David
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911460/
https://www.ncbi.nlm.nih.gov/pubmed/20598132
http://dx.doi.org/10.1186/1471-2105-11-368