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Three-Dimensional Structure of TspO by Electron Cryomicroscopy of Helical Crystals

The 18 kDa TSPO protein is a polytopic mitochondrial outer membrane protein involved in a wide range of physiological functions and pathologies, including neurodegeneration and cancer. The pharmacology of TSPO has been extensively studied, but little is known about its biochemistry, oligomeric state...

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Detalles Bibliográficos
Autores principales: Korkhov, Vladimir M., Sachse, Carsten, Short, Judith M., Tate, Christopher G.
Formato: Texto
Lenguaje:English
Publicado: Cell Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911597/
https://www.ncbi.nlm.nih.gov/pubmed/20541505
http://dx.doi.org/10.1016/j.str.2010.03.001