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Three-Dimensional Structure of TspO by Electron Cryomicroscopy of Helical Crystals
The 18 kDa TSPO protein is a polytopic mitochondrial outer membrane protein involved in a wide range of physiological functions and pathologies, including neurodegeneration and cancer. The pharmacology of TSPO has been extensively studied, but little is known about its biochemistry, oligomeric state...
Autores principales: | Korkhov, Vladimir M., Sachse, Carsten, Short, Judith M., Tate, Christopher G. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911597/ https://www.ncbi.nlm.nih.gov/pubmed/20541505 http://dx.doi.org/10.1016/j.str.2010.03.001 |
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