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Sar1 assembly regulates membrane constriction and ER export

The guanosine triphosphatase Sar1 controls the assembly and fission of COPII vesicles. Sar1 utilizes an amphipathic N-terminal helix as a wedge that inserts into outer membrane leaflets to induce vesicle neck constriction and control fission. We hypothesize that Sar1 organizes on membranes to contro...

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Detalles Bibliográficos
Autores principales: Long, Kimberly R., Yamamoto, Yasunori, Baker, Adam L., Watkins, Simon C., Coyne, Carolyn B., Conway, James F., Aridor, Meir
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911667/
https://www.ncbi.nlm.nih.gov/pubmed/20624903
http://dx.doi.org/10.1083/jcb.201004132