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Calmodulin-dependent nuclear import of HMG-box family nuclear factors: importance of the role of SRY in sex reversal
The HMG (high-mobility group)-box-containing chromatin-remodelling factor SRY (sex-determining region on the Y chromosome) plays a key role in sex determination. Its role in the nucleus is critically dependent on two NLSs (nuclear localization signals) that flank its HMG domain: the C-terminally loc...
Autores principales: | Kaur, Gurpreet, Delluc-Clavieres, Aurelie, Poon, Ivan K. H., Forwood, Jade K., Glover, Dominic J., Jans, David A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911679/ https://www.ncbi.nlm.nih.gov/pubmed/20528776 http://dx.doi.org/10.1042/BJ20091758 |
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