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Bench-to-bedside review: The role of β-lactamases in antibiotic-resistant Gram-negative infections

Multidrug resistance has been increasing among Gram-negative bacteria and is strongly associated with the production of both chromosomal- and plasmid-encoded β-lactamases, whose number now exceeds 890. Many of the newer enzymes exhibit broad-spectrum hydrolytic activity against most classes of β-lac...

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Detalles Bibliográficos
Autor principal: Bush, Karen
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911681/
https://www.ncbi.nlm.nih.gov/pubmed/20594363
http://dx.doi.org/10.1186/cc8892