Influence of genetic variations in TLR4 and TIRAP/Mal on the course of sepsis and pneumonia and cytokine release: an observational study in three cohorts

INTRODUCTION: It has been proposed that individual genetic variation contributes to the course of severe infections and sepsis. Recent studies of single nucleotide polymorphisms (SNPs) within the endotoxin receptor and its signaling system showed an association with the risk of disease development....

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Detalles Bibliográficos
Autores principales: Kumpf, Oliver, Giamarellos-Bourboulis, Evangelos J, Koch, Alexander, Hamann, Lutz, Mouktaroudi, Maria, Oh, Djin-Ye, Latz, Eicke, Lorenz, Eva, Schwartz, David A, Ferwerda, Bart, Routsi, Christina, Skalioti, Chryssanthi, Kullberg, Bart-Jan, van der Meer, Jos WM, Schlag, Peter M, Netea, Mihai G, Zacharowski, Kai, Schumann, Ralf R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911747/
https://www.ncbi.nlm.nih.gov/pubmed/20525286
http://dx.doi.org/10.1186/cc9047

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911747/
https://www.ncbi.nlm.nih.gov/pubmed/20525286
http://dx.doi.org/10.1186/cc9047

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