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A multi-center, randomized, double-blind, parallel, placebo-controlled trial to evaluate the efficacy, safety, and pharmacokinetics of intravenous ibuprofen for the treatment of fever in critically ill and non-critically ill adults

INTRODUCTION: Hospitalized patients are often unable to ingest or tolerate oral antipyretics and recently an aqueous formulation of intravenous (IV) ibuprofen was approved by the US-FDA for the reduction of fever in adults. METHODS: We evaluated IV ibuprofen to reduce fever exceeding 101.0°F, measur...

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Detalles Bibliográficos
Autores principales: Morris, Peter E, Promes, John T, Guntupalli, Kalpalatha K, Wright, Patrick E, Arons, Murray M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911773/
https://www.ncbi.nlm.nih.gov/pubmed/20591173
http://dx.doi.org/10.1186/cc9089