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Monocyte surface expression of Fcγ receptor RI (CD64), a biomarker reflecting type-I interferon levels in systemic lupus erythematosus

INTRODUCTION: More than half of systemic lupus erythematosus (SLE) patients show evidence of excess type I interferon (IFN-I) production, a phenotype associated with renal disease and certain autoantibodies. However, detection of IFN-I proteins in serum is unreliable, and the measurement of interfer...

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Detalles Bibliográficos
Autores principales: Li, Yi, Lee, Pui Y, Kellner, Erinn S, Paulus, Matthew, Switanek, Juliana, Xu, Yuan, Zhuang, Haoyang, Sobel, Eric S, Segal, Mark S, Satoh, Minoru, Reeves, Westley H
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911874/
https://www.ncbi.nlm.nih.gov/pubmed/20478071
http://dx.doi.org/10.1186/ar3017