Physiological tonicity improves human chondrogenic marker expression through nuclear factor of activated T-cells 5 in vitro

INTRODUCTION: Chondrocytes experience a hypertonic environment compared with plasma (280 mOsm) due to the high fixed negative charge density of cartilage. Standard isolation of chondrocytes removes their hypertonic matrix, exposing them to nonphysiological conditions. During in vitro expansion, chon...

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Detalles Bibliográficos
Autores principales: van der Windt, Anna E, Haak, Esther, Das, Ruud HJ, Kops, Nicole, Welting, Tim JM, Caron, Marjolein MJ, van Til, Niek P, Verhaar, Jan AN, Weinans, Harrie, Jahr, Holger
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911888/
https://www.ncbi.nlm.nih.gov/pubmed/20492652
http://dx.doi.org/10.1186/ar3031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911888/
https://www.ncbi.nlm.nih.gov/pubmed/20492652
http://dx.doi.org/10.1186/ar3031

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