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Toll-like receptor 3 upregulation in macrophages participates in the initiation and maintenance of pristane-induced arthritis in rats

INTRODUCTION: Toll-like receptors (TLRs) are involved in both innate and adaptive immune responses and are likely to play a complex role in the pathogenesis of human rheumatoid arthritis (RA) and experimental arthritis. The objective of this study was to identify the key TLR in pristane-induced arth...

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Detalles Bibliográficos
Autores principales: Meng, Liesu, Zhu, Wenhua, Jiang, Congshan, He, Xiaojing, Hou, Weikun, Zheng, Fang, Holmdahl, Rikard, Lu, Shemin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911891/
https://www.ncbi.nlm.nih.gov/pubmed/20500834
http://dx.doi.org/10.1186/ar3034