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Only one independent genetic association with rheumatoid arthritis within the KIAA1109-TENR-IL2-IL21 locus in Caucasian sample sets: confirmation of association of rs6822844 with rheumatoid arthritis at a genome-wide level of significance

INTRODUCTION: The single nucleotide polymorphism (SNP) rs6822844 within the KIAA1109-TENR-IL2-IL21 gene cluster has been associated with rheumatoid arthritis (RA). Other variants within this cluster, including rs17388568 that is not in linkage disequilibrium (LD) with rs6822844, and rs907715 that is...

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Detalles Bibliográficos
Autores principales: Hollis-Moffatt, Jade E, Chen-Xu, Michael, Topless, Ruth, Dalbeth, Nicola, Gow, Peter J, Harrison, Andrew A, Highton, John, Jones, Peter BB, Nissen, Michael, Smith, Malcolm D, van Rij, Andre, Jones, Gregory T, Stamp, Lisa K, Merriman, Tony R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911910/
https://www.ncbi.nlm.nih.gov/pubmed/20553587
http://dx.doi.org/10.1186/ar3053