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Synapses, Synaptic Activity and Intraneuronal Aβ in Alzheimer's Disease
β-Amyloid peptide accumulation plays a central role in the pathogenesis of Alzheimer's disease. Aberrant β-amyloid buildup in the brain has been shown to be present both in the extracellular space and within neurons. Synapses are important targets of β-amyloid, and alterations in synapses bette...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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Frontiers Research Foundation
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912028/ https://www.ncbi.nlm.nih.gov/pubmed/20725518 http://dx.doi.org/10.3389/fnagi.2010.00013 |