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Synapses, Synaptic Activity and Intraneuronal Aβ in Alzheimer's Disease

β-Amyloid peptide accumulation plays a central role in the pathogenesis of Alzheimer's disease. Aberrant β-amyloid buildup in the brain has been shown to be present both in the extracellular space and within neurons. Synapses are important targets of β-amyloid, and alterations in synapses bette...

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Detalles Bibliográficos
Autores principales: Tampellini, Davide, Gouras, Gunnar K.
Formato: Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912028/
https://www.ncbi.nlm.nih.gov/pubmed/20725518
http://dx.doi.org/10.3389/fnagi.2010.00013