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Lack of effects of typical and atypical antipsychotics in DARPP-32 and NCS-1 levels in PC12 cells overexpressing NCS-1

BACKGROUND: Schizophrenia is the major psychiatry disorder, which the exact cause remains unknown. However, it is well known that dopamine-mediated neurotransmission imbalance is associated with this pathology and the main target of antipsychotics is the dopamine receptor D(2). Recently, it was desc...

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Detalles Bibliográficos
Autores principales: Souza, Bruno R, Torres, Karen CL, Miranda, Débora M, Motta, Bernardo S, Scotti-Muzzi, Estêvão, Guimarães, Melissa M, Carneiro, Daniel S, Rosa, Daniela VF, Souza, Renan P, Reis, Helton J, Jeromin, Andreas, Romano-Silva, Marco A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912242/
https://www.ncbi.nlm.nih.gov/pubmed/20565907
http://dx.doi.org/10.1186/1477-5751-9-4