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Identification of target genes for wild type and truncated HMGA2 in mesenchymal stem-like cells

BACKGROUND: The HMGA2 gene, coding for an architectural transcription factor involved in mesenchymal embryogenesis, is frequently deranged by translocation and/or amplification in mesenchymal tumours, generally leading to over-expression of shortened transcripts and a truncated protein. METHODS: To...

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Detalles Bibliográficos
Autores principales: Henriksen, Jørn, Stabell, Marianne, Meza-Zepeda, Leonardo A, Lauvrak, Silje AU, Kassem, Moustapha, Myklebost, Ola
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912264/
https://www.ncbi.nlm.nih.gov/pubmed/20576167
http://dx.doi.org/10.1186/1471-2407-10-329