Common ADRB2 Haplotypes Derived from 26 Polymorphic Sites Direct β(2)-Adrenergic Receptor Expression and Regulation Phenotypes

BACKGROUND: The β(2)-adrenergic receptor (β(2)AR) is expressed on numerous cell-types including airway smooth muscle cells and cardiomyocytes. Drugs (agonists or antagonists) acting at these receptors for treatment of asthma, chronic obstructive pulmonary disease, and heart failure show substantial...

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Detalles Bibliográficos
Autores principales: Panebra, Alfredo, Wang, Wayne C., Malone, Molly M., Pitter, Demar R. G., Weiss, Scott T., Hawkins, Gregory A., Liggett, Stephen B.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912278/
https://www.ncbi.nlm.nih.gov/pubmed/20686604
http://dx.doi.org/10.1371/journal.pone.0011819

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912278/
https://www.ncbi.nlm.nih.gov/pubmed/20686604
http://dx.doi.org/10.1371/journal.pone.0011819

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