Cargando…

Common ADRB2 Haplotypes Derived from 26 Polymorphic Sites Direct β(2)-Adrenergic Receptor Expression and Regulation Phenotypes

BACKGROUND: The β(2)-adrenergic receptor (β(2)AR) is expressed on numerous cell-types including airway smooth muscle cells and cardiomyocytes. Drugs (agonists or antagonists) acting at these receptors for treatment of asthma, chronic obstructive pulmonary disease, and heart failure show substantial...

Descripción completa

Detalles Bibliográficos
Autores principales:	Panebra, Alfredo, Wang, Wayne C., Malone, Molly M., Pitter, Demar R. G., Weiss, Scott T., Hawkins, Gregory A., Liggett, Stephen B.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912278/ https://www.ncbi.nlm.nih.gov/pubmed/20686604 http://dx.doi.org/10.1371/journal.pone.0011819

Ejemplares similares

β(2)-Adrenergic Receptor (ADRB2) Gene Polymorphisms and Risk of COPD Exacerbations: The Rotterdam Study
por: Karimi, Leila, et al.
Publicado: (2019)

Investigating changes in β-adrenergic gene expression (ADRB1 and ADRB2) in Takotsubo (stress) cardiomyopathy syndrome; a pilot study
por: Tutgun Onrat, Serap, et al.
Publicado: (2021)

Effect of β(2)-adrenergic receptor gene (ADRB2) 3′ untranslated region polymorphisms on inhaled corticosteroid/long-acting β(2)-adrenergic agonist response
por: Ambrose, Helen J, et al.
Publicado: (2012)

Beta-2 Adrenergic Receptor (ADRB2) Gene Polymorphisms and the Risk of Asthma: A Meta-Analysis of Case-Control Studies
por: Liang, Si-Qiao, et al.
Publicado: (2014)

Correction to: Investigating changes in β‑adrenergic gene expression (ADRB1 and ADRB2) in Takotsubo (stress) cardiomyopathy syndrome; a pilot study
por: Onrat, Serap Tutgun, et al.
Publicado: (2022)

Human-Specific SNP in Obesity Genes, Adrenergic Receptor Beta2 (ADRB2), Beta3 (ADRB3), and PPAR γ2 (PPARG), during Primate Evolution
por: Takenaka, Akiko, et al.
Publicado: (2012)

Association of ADRB2 polymorphism with triglyceride levels in Tongans
por: Naka, Izumi, et al.
Publicado: (2013)

Genetic Polymorphisms in ADRB2 and ADRB1 Are Associated with Differential Survival in Heart Failure Patients Taking β-Blockers
por: Guerra, Leonardo A., et al.
Publicado: (2022)

The C79G Polymorphism of the β2-Adrenergic Receptor Gene, ADRB2, and Susceptibility to Pediatric Asthma: Meta-Analysis from Review of the Literature
por: Zhang, Yan-Qin, et al.
Publicado: (2019)

A functional SNP upstream of the beta-2 adrenergic receptor gene (ADRB2) is associated with obesity in Oceanic populations
por: Naka, I, et al.
Publicado: (2013)

Molecular Characterization and Expression Analysis of Adrenergic Receptor Beta 2 (ADRB2) Gene before and after Exercise in the Horse
por: Cho, Hyun-Woo, et al.
Publicado: (2015)

Expression of the beta-2 adrenergic receptor (ADRB-2) in human and monkey ovarian follicles: a marker of growing follicles?
por: Merz, Christoph, et al.
Publicado: (2015)

ADRB2 Gene Polymorphisms and Salbutamol Responsiveness in Serbian Children with Asthma
por: Jovicic, N, et al.
Publicado: (2018)

Obesity-related gene ADRB2, ADRB3 and GHRL polymorphisms and the response to a weight loss diet intervention in adult women
por: Saliba, Louise F., et al.
Publicado: (2014)

ADRB2 polymorphisms predict the risk of myocardial infarction and coronary artery disease
por: Wang, Dong-Wei, et al.
Publicado: (2015)

PPARgamma-2 and ADRB3 polymorphisms in connective tissue diseases and lipid disorders
por: Grygiel-Górniak, Bogna, et al.
Publicado: (2018)

Association of ADRB2 gene polymorphisms and intestinal microbiota in Chinese Han adolescents
por: Xu, Shanrong, et al.
Publicado: (2023)

Beta2-Adrenergic Receptor Polymorphisms and Haplotypes Associate With Chronic Pain in Sickle Cell Disease
por: Jhun, Ellie H., et al.
Publicado: (2019)

ADRB2 Arg16Gly Polymorphism, Lung Function, and Mortality: Results from the Atherosclerosis Risk in Communities Study
por: Ferdinands, Jill M., et al.
Publicado: (2007)

Polymorphisms in ADRB2 gene can modulate the response to bronchodilators and the severity of cystic fibrosis
por: Marson, Fernando A L, et al.
Publicado: (2012)

ADRB2-Targeting Therapies for Prostate Cancer
por: Kulik, George
Publicado: (2019)

Association of beta3-adrenergic receptor (ADRB3) Trp64Arg gene polymorphism with obesity and metabolic syndrome in the Balinese: a pilot study
por: Malik, Safarina G, et al.
Publicado: (2011)

ADRB3 Polymorphism Associated with BMI Gain in Japanese Men
por: Takeuchi, Shouhei, et al.
Publicado: (2012)

Functional Polymorphism in the ADRB3 Gene, Encoding the Beta-3 Adrenergic Receptor, and Response to Intra-Detrusor Injection of Botulinum Toxin-A in Women with Overactive Bladder
por: Ciećwież, Sylwester Michał, et al.
Publicado: (2022)

P51 - ADRB2 gene polymorphisms of the asthma pediatric patients in Russia’s Perm region
por: Furman, Evgenii, et al.
Publicado: (2014)

Genetic variability of five ADRB2 polymorphisms among Mexican Amerindian ethnicities and the Mestizo population
por: Salas-Martínez, María Guadalupe, et al.
Publicado: (2019)

Thyrotoxic Periodic Paralysis and Polymorphisms of the ADRB2, AR, and GABRA3 Genes in Men with Graves Disease
por: Park, Suyeon, et al.
Publicado: (2016)

No Consistent Effect of ADRB2 Haplotypes on Obesity, Hypertension and Quantitative Traits of Body Fatness and Blood Pressure among 6,514 Adult Danes
por: Gjesing, Anette P., et al.
Publicado: (2009)

Direct molecular haplotyping by melting curve analysis of hybridization probes: beta 2-adrenergic receptor haplotypes as an example
por: Pont-Kingdon, Genevieve, et al.
Publicado: (2005)

Obesity is associated with the Arg389Gly ADRB1 but not with the Trp64Arg ADRB3 polymorphism in children from San Luis Potosí and León, México
por: Aradillas-García, Celia, et al.
Publicado: (2017)

Effects of GRK5 and ADRB1 polymorphisms influence on systolic heart failure
por: Kang, Sheng, et al.
Publicado: (2015)

The Trp64Arg polymorphism in β3 adrenergic receptor (ADRB3) gene is associated with adipokines and plasma lipids: a systematic review, meta-analysis, and meta-regression
por: Luo, Zhi, et al.
Publicado: (2020)

Expression of ADRB2 in children with neuroblastoma and its influence on prognosis
por: Cao, Lijian, et al.
Publicado: (2022)

Commentary: Interaction of the ADRB2 Gene Polymorphism with Childhood Trauma in Predicting Adult Symptoms of Posttraumatic Stress Disorder
por: Ghitza, Udi E.
Publicado: (2015)

Transcription Factor E2F1 Regulates the Expression of ADRB2
por: Du, Juan, et al.
Publicado: (2023)

A functional SNP upstream of the ADRB2 gene is associated with COPD
por: Li, Jin-Xiu, et al.
Publicado: (2018)

ADRB3, ROCK2, and GEF Levels in Overactive Bladder Patients
por: Fırat, Elif, et al.
Publicado: (2022)

Activation of ADRB2/PKA Signaling Pathway Facilitates Lipid Synthesis in Meibocytes, and Beta-Blocker Glaucoma Drug Impedes PKA-Induced Lipid Synthesis by Inhibiting ADRB2
por: Jun, Ikhyun, et al.
Publicado: (2022)

Polymorphisms in the ADRB2 gene and Graves disease: a case-control study and a meta-analysis of available evidence
por: Chu, Xun, et al.
Publicado: (2009)

Association of polymorphism genes LPL, ADRB2, AGT and AGTR1 with risk of hyperinsulinism and insulin resistance in the Kazakh population
por: Shakhanova, Aizhan, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_49h7l340ue9conppu4sd19pbni