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Stat3 Activates the Receptor Tyrosine Kinase Like Orphan Receptor-1 Gene in Chronic Lymphocytic Leukemia Cells

BACKGROUND: The receptor tyrosine kinase like orphan receptor (ROR)-1 gene is overexpressed in chronic lymphocytic leukemia (CLL). Because Stat3 is constitutively activated in CLL and sequence analysis revealed that the ROR1 promoter harbors γ-interferon activation sequence-like elements typically a...

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Detalles Bibliográficos
Autores principales: Li, Ping, Harris, David, Liu, Zhiming, Liu, Jie, Keating, Michael, Estrov, Zeev
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912280/
https://www.ncbi.nlm.nih.gov/pubmed/20686606
http://dx.doi.org/10.1371/journal.pone.0011859