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An integrated Bayesian analysis of LOH and copy number data

BACKGROUND: Cancer and other disorders are due to genomic lesions. SNP-microarrays are able to measure simultaneously both genotype and copy number (CN) at several Single Nucleotide Polymorphisms (SNPs) along the genome. CN is defined as the number of DNA copies, and the normal is two, since we have...

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Detalles Bibliográficos
Autores principales: Rancoita, Paola MV, Hutter, Marcus, Bertoni, Francesco, Kwee, Ivo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912301/
https://www.ncbi.nlm.nih.gov/pubmed/20550648
http://dx.doi.org/10.1186/1471-2105-11-321