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An integrated Bayesian analysis of LOH and copy number data
BACKGROUND: Cancer and other disorders are due to genomic lesions. SNP-microarrays are able to measure simultaneously both genotype and copy number (CN) at several Single Nucleotide Polymorphisms (SNPs) along the genome. CN is defined as the number of DNA copies, and the normal is two, since we have...
Autores principales: | Rancoita, Paola MV, Hutter, Marcus, Bertoni, Francesco, Kwee, Ivo |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912301/ https://www.ncbi.nlm.nih.gov/pubmed/20550648 http://dx.doi.org/10.1186/1471-2105-11-321 |
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