HPeak: an HMM-based algorithm for defining read-enriched regions in ChIP-Seq data

BACKGROUND: Protein-DNA interaction constitutes a basic mechanism for the genetic regulation of target gene expression. Deciphering this mechanism has been a daunting task due to the difficulty in characterizing protein-bound DNA on a large scale. A powerful technique has recently emerged that coupl...

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Detalles Bibliográficos
Autores principales: Qin, Zhaohui S, Yu, Jianjun, Shen, Jincheng, Maher, Christopher A, Hu, Ming, Kalyana-Sundaram, Shanker, Yu, Jindan, Chinnaiyan, Arul M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912305/
https://www.ncbi.nlm.nih.gov/pubmed/20598134
http://dx.doi.org/10.1186/1471-2105-11-369

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912305/
https://www.ncbi.nlm.nih.gov/pubmed/20598134
http://dx.doi.org/10.1186/1471-2105-11-369

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