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HPeak: an HMM-based algorithm for defining read-enriched regions in ChIP-Seq data
BACKGROUND: Protein-DNA interaction constitutes a basic mechanism for the genetic regulation of target gene expression. Deciphering this mechanism has been a daunting task due to the difficulty in characterizing protein-bound DNA on a large scale. A powerful technique has recently emerged that coupl...
| Autores principales: | , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912305/ https://www.ncbi.nlm.nih.gov/pubmed/20598134 http://dx.doi.org/10.1186/1471-2105-11-369 |