The heparan sulfate co-receptor and the concentration of fibroblast growth factor-2 independently elicit different signalling patterns from the fibroblast growth factor receptor

BACKGROUND: The fibroblast growth factor receptor (FGFR) interprets concentration gradients of FGF ligands and structural changes in the heparan sulfate (HS) co-receptor to generate different cellular responses. However, whether the FGFR generates different signals is not known. RESULTS: We have pre...

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Detalles Bibliográficos
Autores principales: Zhu, Hongyan, Duchesne, Laurence, Rudland, Philip S, Fernig, David G
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912315/
https://www.ncbi.nlm.nih.gov/pubmed/20576134
http://dx.doi.org/10.1186/1478-811X-8-14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912315/
https://www.ncbi.nlm.nih.gov/pubmed/20576134
http://dx.doi.org/10.1186/1478-811X-8-14

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