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The heparan sulfate co-receptor and the concentration of fibroblast growth factor-2 independently elicit different signalling patterns from the fibroblast growth factor receptor

BACKGROUND: The fibroblast growth factor receptor (FGFR) interprets concentration gradients of FGF ligands and structural changes in the heparan sulfate (HS) co-receptor to generate different cellular responses. However, whether the FGFR generates different signals is not known. RESULTS: We have pre...

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Detalles Bibliográficos
Autores principales:	Zhu, Hongyan, Duchesne, Laurence, Rudland, Philip S, Fernig, David G
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912315/ https://www.ncbi.nlm.nih.gov/pubmed/20576134 http://dx.doi.org/10.1186/1478-811X-8-14

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