Cargando…
Quantifying the Proteolytic Release of Extracellular Matrix-Sequestered VEGF with a Computational Model
BACKGROUND: VEGF proteolysis by plasmin or matrix metalloproteinases (MMPs) is believed to play an important role in regulating vascular patterning in vivo by releasing VEGF from the extracellular matrix (ECM). However, a quantitative understanding of the kinetics of VEGF cleavage and the efficiency...
| Autores principales: | , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912330/ https://www.ncbi.nlm.nih.gov/pubmed/20686621 http://dx.doi.org/10.1371/journal.pone.0011860 |