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Role of Endoplasmic Reticulum Stress in α-TEA Mediated TRAIL/DR5 Death Receptor Dependent Apoptosis

BACKGROUND: α-TEA (RRR-α-tocopherol ether-linked acetic acid analog), a derivative of RRR-α-tocopherol (vitamin E) exhibits anticancer actions in vitro and in vivo in variety of cancer types. The objective of this study was to obtain additional insights into the mechanisms involved in α-TEA induced...

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Detalles Bibliográficos
Autores principales: Tiwary, Richa, Yu, Weiping, Li, Jing, Park, Sook-Kyung, Sanders, Bob G., Kline, Kimberly
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912340/
https://www.ncbi.nlm.nih.gov/pubmed/20686688
http://dx.doi.org/10.1371/journal.pone.0011865