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Calpain 8/nCL-2 and Calpain 9/nCL-4 Constitute an Active Protease Complex, G-Calpain, Involved in Gastric Mucosal Defense

Calpains constitute a superfamily of Ca(2+)-dependent cysteine proteases, indispensable for various cellular processes. Among the 15 mammalian calpains, calpain 8/nCL-2 and calpain 9/nCL-4 are predominantly expressed in the gastrointestinal tract and are restricted to the gastric surface mucus (pit)...

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Detalles Bibliográficos
Autores principales: Hata, Shoji, Abe, Manabu, Suzuki, Hidenori, Kitamura, Fujiko, Toyama-Sorimachi, Noriko, Abe, Keiko, Sakimura, Kenji, Sorimachi, Hiroyuki
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912385/
https://www.ncbi.nlm.nih.gov/pubmed/20686710
http://dx.doi.org/10.1371/journal.pgen.1001040