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Requirement of Male-Specific Dosage Compensation in Drosophila Females—Implications of Early X Chromosome Gene Expression

Dosage compensation equates between the sexes the gene dose of sex chromosomes that carry substantially different gene content. In Drosophila, the single male X chromosome is hypertranscribed by approximately two-fold to effect this correction. The key genes are male lethal and appear not to be requ...

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Detalles Bibliográficos
Autores principales: Gladstein, Natalie, McKeon, Meghan N., Horabin, Jamila I.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912388/
https://www.ncbi.nlm.nih.gov/pubmed/20686653
http://dx.doi.org/10.1371/journal.pgen.1001041