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Oseltamivir–Resistant Pandemic H1N1/2009 Influenza Virus Possesses Lower Transmissibility and Fitness in Ferrets

The neuraminidase (NA) inhibitor oseltamivir offers an important immediate option for the control of influenza, and its clinical use has increased substantially during the recent H1N1 pandemic. In view of the high prevalence of oseltamivir-resistant seasonal H1N1 influenza viruses in 2007–2008, ther...

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Detalles Bibliográficos
Autores principales: Duan, Susu, Boltz, David A., Seiler, Patrick, Li, Jiang, Bragstad, Karoline, Nielsen, Lars P., Webby, Richard J., Webster, Robert G., Govorkova, Elena A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912389/
https://www.ncbi.nlm.nih.gov/pubmed/20686654
http://dx.doi.org/10.1371/journal.ppat.1001022