The Meningococcal Vaccine Candidate Neisserial Surface Protein A (NspA) Binds to Factor H and Enhances Meningococcal Resistance to Complement

Complement forms an important arm of innate immunity against invasive meningococcal infections. Binding of the alternative complement pathway inhibitor factor H (fH) to fH-binding protein (fHbp) is one mechanism meningococci employ to limit complement activation on the bacterial surface. fHbp is a l...

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Detalles Bibliográficos
Autores principales: Lewis, Lisa A., Ngampasutadol, Jutamas, Wallace, Ruth, Reid, Jane E. A., Vogel, Ulrich, Ram, Sanjay
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912398/
https://www.ncbi.nlm.nih.gov/pubmed/20686663
http://dx.doi.org/10.1371/journal.ppat.1001027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912398/
https://www.ncbi.nlm.nih.gov/pubmed/20686663
http://dx.doi.org/10.1371/journal.ppat.1001027

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